Although humans are not the primary hosts for WNV, they may become infected through a mosquito bite. Most infections are usually asymptomatic, however the virus can be transmitted through blood, tissue and organ donations.
Transmission of WNV can pose particular danger for immunocompromised patients, causing neuroinvasive complications such as meningitis,encephalitis, meningoencephalitis, or acute flaccid paralysis, which can lead to irreversible neurological damage, coma, and death.1
To enable early and accurate detection of WNV, Roche Molecular offers the cobas® TaqScreen Wst Nile Virus Test and cobas® West Nile Virus test for the direct detection of WNV RNA for donor screening and provides broad coverage for other flaviviruses that cause transfusion-transmitted infectious diseases.
- Petersen LR, Brault AC, Nasci RS. West Nile virus: review of the literature. JAMA. 2013;310:308-315.